DEVELOPMENT OF AN ADAPTABLE QUALIFICATION TEST SET FOR PERSONNEL INVOLVED IN VISUAL INSPECTION PROCEDURES OF PARENTERAL DRUG PRODUCTS MANUFACTURED UNDER GOOD MANUFACTURING PRACTICE CONDITIONS IN HOSPITAL PHARMACY COMPOUNDING FACILITIES

Development of an Adaptable Qualification Test Set for Personnel Involved in Visual Inspection Procedures of Parenteral Drug Products Manufactured Under Good Manufacturing Practice Conditions in Hospital Pharmacy Compounding Facilities

Objectives: Parenteral drug products manufactured under GMP conditions should be visually inspected for defects and particulate contamination by trained and qualified personnel.Although personnel qualification is required, no practical protocols or formal guidelines are available for the development of qualification test sets (QTSs) used for qualif

read more

Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response.

RNA interference (RNAi) is an antiviral pathway common to many eukaryotes that detects and cleaves foreign nucleic acids.In mammals, mitochondrially localized proteins such as mitochondrial antiviral signaling (MAVS), retinoic acid-inducible gene I (RIG-I), and melanoma hindigyanvishv.com differentiation-associated protein 5 (MDA5) mediate antivira

read more


Brain network clustering with information flow motifs

Abstract Recent work has revealed frequency-dependent global patterns of information flow by a network analysis of magnetoencephalography data of the human brain.However, it is unknown which properties on a small subgraph-scale of those functional brain networks are dominant at different frequencies bands.Motifs are the building blocks of networks

read more